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KMID : 0380620110430030375
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Korean Journal of Food Science and Technology
2011 Volume.43 No. 3 p.375 ~ p.380
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Cholesterol Improvement Effects of Fermented Defatted Soybean Grits Added to Corchorus olitorius
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Kim Hyun-Jeong
Lee Sung-Gyu
Lee Sam-Pin
Lee In-Seon
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Abstract
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This study was performed to investigate cholesterol improvement effects of adding fermented defatted soybean grit (FD) and FD added to 5 or 10% Corchorus olitorius (FDC). Cholesterol adsorption in the FD and FDC group was more than 70%. Apolipoprotein AI and CIII improved in HepG2 cells, and a greater improvement effect was shown in FDC than that in FD. We also investigated the effect of FDC on body lipid metabolism and a high-fat diet for 4 weeks. Rats were divided into control (Con), high-fat (HF), HF treated with 20% FD (HF-FD), and HF treated with 20% FDC (HF-FDC) groups. Plasma total cholesterol and low density lipoprotein-cholesterol concentrations, hepatic total cholesterol, and triglyceride contents were significantly lower in the HF-FDC group than those in the HF group. Additionally, fecal total cholesterol and triglyceride contents increased in rats treated with FDC. Hepatic 3-hydroxy-3-methylglutaryl-coenzyme A reductase activities were significantly lower in the HF-FDC group than those in the HF group.
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KEYWORD
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defatted soybean grit, Corchorus olitorius, hypercholesterol, HMG-CoA reductase
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